Document Type
Article
Publication Date
6-1-2012
Abstract
The rhizomes of Zingiber spectabile yielded a new dimeric flavonol glycoside for which the name kaempferol-3-O-(4″-O-acetyl)-α-l-rhamnopyranoside-(I-6,II-8)-kaempferol-3-O-(4″-O-acetyl)-α-l-rhamnopyranoside; spectaflavoside A (1) was proposed, along with kaempferol and its four acetylrhamnosides (2–6), demethoxycurcumin (7) and curcumin (8). The structure of spectaflavoside A was elucidated by spectroscopic methods including, 1D and 2D NMR techniques. This is the first report on the occurrence of a dimeric flavonol glycoside in the Zingiberaceae and the second in nature. Spectaflavoside A was found to be a potent iron chelating agent.
Keywords
Zingiber spectabile Griff., Zingiberaceae, Dimeric flavonol glycoside, Bisflavonol glycoside, Spectaflavoside A, Iron chelating activity
Divisions
fac_med
Funders
Research University Grant RG 017/09 SUS and RG 008-09B10 ,16-02-03-6024 provided by MOSTI ,05-01-05SF01001 Escience Fund provided by the Ministry of Agriculture and Agro-based Industry Malaysia
Publication Title
Bioorganic & Medicinal Chemistry Letters
Volume
22
Issue
11
Publisher
Elsevier