Document Type
Article (Restricted)
Publication Date
1-1-2011
Abstract
Four new linearly fused bisindole alkaloids, lumutinines A−D (1−4), were isolated from the stem-bark extract of Alstonia macrophylla. Lumutinines A (1) and B (2) represent the first examples of linear, ring A/F-fused macroline−macroline-type bisindoles, while lumutinines C (3) and D (4) were constituted from the union of macroline and sarpagine moieties. A reinvestigation of the stereochemical assignment of alstoumerine (8) by NMR and X-ray diffraction analyses indicated that the configuration at C-16 and C-19 required revision.
Keywords
Alstonia, Lumutinine, NMR
Divisions
CHEMISTRY
Publication Title
Journal of Natural Products
Volume
74
Publisher
American Chemical Society and American Society of Pharmacognosy
Additional Information
Department of Chemistry, University of Malaya
COinS