Date of Award

1-1-2001

Thesis Type

Masters

Document Type

Thesis

Divisions

Faculty of Science

Department

Department of Chemistry

Institution

Universiti Malaya

Abstract

The chemical content of the 'leaves and bark of Des mos dumosus has been carried out in this study. The leaves yielded nine isoquinoline type of alkaloids and two flavones. The isoquinoline alkaloids isolated were pronuciferine 37, stepharine 39, nomuciferine 40, (-) - 3 - hydroxynomuciferine 41, norlirioferine 42, asimilobine 43, liriodenine 44, lysicamine 45 and O - methylmoschatoline 46. The flavones were 5 - hydroxy - 6,7 - dimethoxyflavone 47 and 5 - hydroxy - 7,8 - dimethoxyflavone 48. The same flavones, 47 and 48 and the alkaloids 45 and 46 were also present in the bark of this species. Another two isoquinoline alkaloids, namely O - methylisopiline 49 and discretamine 50, were found only in the bark of Desmos dumosus. All the above compounds were isolated by using chromatographic techniques, whereas the structural formula of the isolated compounds were elucidated using spectroscopic methods such as 1H NMR, 13C NMR, COS.Y, MS, IR and UV.

Initial

snms

Additional Information

Dissertation (M.A) -- Faculty of Science, Universiti Malaya, 1999.

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