Massive pleural effusions in cryptococcal meningitis.

Document Type

Article

Publication Date

5-1-1999

Abstract

Cryptococcal infection uncommonly presents with pulmonary manifestations and even more rarely so as massive bilateral effusions. Pleural involvement is usually associated with underlying pulmonary parenchymal lesions and is unusual while on antifungal therapy. We report a patient with cryptococcal meningitis who, while on intravenous 5-flucytosine and amphotericin B, developed life-threatening bilateral massive pleural effusions with evidence of spontaneous resolution, consistent with prior hypothesis of antigenic stimulation as the cause of pleural involvement.

Keywords

Adult, Amphotericin B/therapeutic use

Divisions

fac_med

Publication Title

Postgraduate medical journal

Volume

75

Issue

883

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