Smart stimuli-responsive nanocarriers for the cancer therapy - nanomedicine
Document Type
Article
Publication Date
8-30-2021
Abstract
Nanomedicine is ongoing current research in the applications of nanotechnology for cancer therapy. Simply from a technology perspective, this field of research has an enormous broadening and success to date. Recently, nanomedicine has also made inroads in the treatment of cancer. Stimuli-responsive nanoparticles are an emerging field of research because its targeting capacity is of great interest in the treatment of cancer. The responsive nano particles are efficient in encountering different internal biological stimuli (acidic, pH, redox, and enzyme) and external stimuli (temperature, ultrasounds, magnetic field, and light), which are used as smart nanocarriers for delivery of the chemotherapeutic and imaging agents for cancer therapy. In-depth, the responsive nanocarrier that responds to the biological cues is of pronounced interest due to its capability to provide a controlled release profile at the tumor-specific site. The outlook of this review focuses on the stimuli-responsive nanocarrier drug delivery systems in sequence to address the biological challenges that need to be evaluated to overcome conventional cancer therapy.
Keywords
Nanocarrier, Stimuli-responsive, Drug delivery, Gene therapy, Targeted therapy, Photodynamic therapy
Divisions
nanotechnology
Funders
Universiti Malaya (RU001-2019),Universiti Malaya (RU001-2020),Universiti Malaya (RU001-2021)
Publication Title
Nanotechnology Reviews
Volume
10
Issue
1
Publisher
Walter de Gruyter GMBH
Publisher Location
GENTHINER STRASSE 13, D-10785 BERLIN, GERMANY