Application of a new choline-imidazole based deep eutectic solvents in hybrid magnetic molecularly imprinted polymer for efficient and selective removal of naproxen from aqueous samples
Document Type
Article
Publication Date
3-1-2021
Abstract
A magnetic molecularly imprinted polymer (Fe3O4@MIP) with naproxen (as template) was successfully prepared by adding a co-solvent consisting of a choline-imidazole based deep eutectic solvent (ChCl-BuIM) during polymerisation. The morphological, functional group, and magnetic characteristics of the synthesised materials were characterised by elemental analysis, Fourier transform-infrared spectroscopy, scanning electron microscopy, and vibrating sample magnetometer. This hybrid Fe3O4@MIP-ChCl-BuIM material was used as a magnetic adsorbent for efficient and selective removal of napmxen from wastewater samples. A batch adsorption study showed that adsorption of naproxen onto the multilayer surface of the adsorbent through a chemisorption mechanism. The data showed that the adsorption was feasible, spontaneous, and exothermic. The Fe3O4@MIP-ChCl-BuIM removed more naproxen (93.2-97.1%) than Fe3O4@MIP without ChCI-BuIM (83.2-88.9%). This finding confirms that the use of ChCl-BuIM improved both the selectivity and affinity of the MIP adsorbent towards naproxen. Competitive recognition studies of the Fe3O4@MIP-ChCl-BuIM using naproxen and structurally similar non-steroidal anti-inflammatory drugs revealed that the Fe3O4@MIP-ChCl-BuIM had high selectivity for naproxen. A cytotoxicity test showed that the synthesised ChCl-BuIM was non-toxic, as the human normal cell lines MCF-10A, and BEAS-2B maintained viability above 50%. These results show that Fe3O4@MIP-ChCl-BuIM has potential for use as a functional adsorption material for the removal of naproxen from water samples.
Keywords
Magnetic molecularly imprinted polymer, Deep eutectic solvents, Naproxen, Wastewater, Removal
Divisions
CHEMISTRY
Funders
Fundamental Research Grant Scheme, Ministry of Higher Education, Malaysia [203.CIPPT.6711661],Universiti Sains Malaysia [304.CIPPT.6316266]
Publication Title
Materials Chemistry and Physics
Volume
261
Publisher
Elsevier
Publisher Location
PO BOX 564, 1001 LAUSANNE, SWITZERLAND