Saccharin: a cheap and mild acidic agent for the synthesis of azo dyes via telescoped dediazotization
Document Type
Article
Publication Date
1-1-2019
Abstract
Green synthesis methods are considered as a safer alternative to the conventional synthetic processes due to their eco-friendly nature, cost-effectiveness, and easy handling. In the present study, an eco-friendly and sustainable method for the synthesis of stable arenediazonium has been developed using saccharin as a cheap and mild acidic agent and tert-butyl nitrite as a diazotization reagent for the first time. These stable intermediates were used in the azo coupling reaction with 4-hydroxybenzaldehyde via telescoped dediazotization. The current method has advantages such as reduced waste by avoiding solvent for the purification of intermediate in diazotization step, cost-effectiveness, simple experimental procedure, good yield of azo dyes, metal-free waste, and environmentally benign conditions. An interesting aspect of this study is the recovery of saccharin from the reaction, which could be reused. © 2019 Walter de Gruyter GmbH, Berlin/Boston.
Keywords
azo coupling, cost-effectiveness, saccharin, stable arenediazonium, sustainable protocol
Divisions
nanotechnology
Funders
High Impact Research Grant (no. RP025A/B/C-14AET) for Scientific Research from University of Malaya, Malaysia
Publication Title
Green Processing and Synthesis
Volume
8
Issue
1
Publisher
De Gruyter