Polyisoprenylated Acylphloroglucinols from Garcinia nervosa
Document Type
Article
Publication Date
1-1-2018
Abstract
Two new polyisoprenylated acylphloroglucinols, 7-epi-isoxanthochymol and 7-epi-cycloxanthochymol (1 – 2), were isolated from the barks of Garcinia nervosa together with their 7-epimers isoxanthochymol (3) and cycloxanthochymol (4). Their structures were determined on the basis of NMR spectroscopic data. The cytotoxic activity of the isolated compounds against HL-60, MCF-7 (human breast adenocarcinoma), A549 (human lung adenocarcinoma) and HepG2 (human hepatocellular carcinoma) cells were evaluated, and all compounds showed cytotoxic activity against all cell lines.
Keywords
Garcinia nervosa, Clusiaceae, Acylphloroglucinols, Cytotoxicity
Divisions
CHEMISTRY
Funders
Japan Society for the Promotion of Science: Grants in-Aid for Scientific Research
Publication Title
Natural Product Communications
Volume
13
Issue
3
Publisher
SAGE Publications