Document Type
Article (Restricted)
Publication Date
1-1-2013
Abstract
Two new indole alkaloids, voatinggine (1) and tabertinggine (2), which are characterized by previously unencountered natural product skeletons,were isolated from a Malayan Tabernaemontana species. The structures and absolute configuration of these alkaloids were determined using NMR and MS analysis, and X-ray diffraction analysis. A possible biogenetic pathway to these novel alkaloids from an iboga precursor, and via a common cleavamine-type intermediate, is presented.
Keywords
Tabernaemontana, Alkaloids, Hexacyclic indole conolutinine, Aspidosperma.
Divisions
CHEMISTRY
Publication Title
Organic Letters
Volume
15
Issue
18
Publisher
American Chemical Society
Additional Information
Department of Chemistry, Faculty of Science, University of Malaya
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