Document Type

Article (Restricted)

Publication Date

1-1-2013

Abstract

The rhizomes of Alpinia pahangensis yielded a new bis-labdanic diterpene for which the name pahangensin C (1) was proposed along with twelve known analogues (2–13). The structure of 1 was elucidated via spectroscopic methods including 1D and 2D NMR techniques and LCMS‑IT‑TOF analysis. Compounds 2 and 12 were isolated for the first time from the genus Alpinia. This is the second occurrence of compounds 2 and 12 in the Zingiberaceae family. Selected analogues exhibited moderate to strong inhibitory activity against Staphylococcus aureus and Bacillus cereus.

Keywords

Alpinia pahangensis, Zingiberaceae, Bis‑labdanic diterpene, Labdane diterpene, Pahangensin C

Divisions

InstituteofBiologicalSciences

Publication Title

Planta Medica

Volume

79

Issue

18

Publisher

Georg Thieme Verlag

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