Document Type
Article (Restricted)
Publication Date
1-1-2012
Abstract
Three unusual natural products, viz., alstopirocine, a macroline alkaloid incorporating a substituted pyrrole moiety, pleiomaltinine, an alkaloide—pyrone adduct, and pleiomalicine, an alkaloid—carbamic acid adduct, were isolated from the Malayan Alstonia angustifolia. The alkaloid moiety in alstopirocine was alstomicine while that in pleiomaltinine and pleiomalicine was pleiocarpamine. The structures were determined by spectroscopic methods and in the case of pleiomaltinine, confirmed by X-ray diffraction analysis. Possible biogenetic pathways to these unusual compounds are presented.
Keywords
Alkaloid—pyrrole, Alkaloid—pyrone, Alkaloid—carbamic acid, Alstonia.
Divisions
CHEMISTRY
Publication Title
Tetrahedron
Volume
66
Publisher
Elsevier
Additional Information
Department of Chemistry, University of Malaya