Document Type

Article (Restricted)

Publication Date

1-1-2012

Abstract

Methodology for the synthesis of alkaloid-pyrones using a novel pyrone annulation of β–carbolines and indoles with 3-siloxy-4-pyrones is reported. The approach has enabled semisynthesis of the unprecedented alkaloid-pyrone pleiomaltinine from the plant-derived indole-alkaloid pleiocarpamine.

Keywords

Alkaloid, Pleiomaltinine, Pyrone, Natural product.

Divisions

CHEMISTRY

Publication Title

Angewandte Chemie International Edition

Volume

51

Publisher

Wiley-VCH Verlag

Additional Information

Department of Chemistry, University of Malaya

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