Document Type

Article (Restricted)

Publication Date

1-1-2010

Abstract

Leucofoline and leuconoline, representing the first members of the aspidospermatan–aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells.

Keywords

Bisindole alkaloids, Leuconotis, NMR, X-ray, Cytotoxicity.

Publication Title

Phytochemistry

ISSN

0031-9422

Divisions

CHEMISTRY

Volume

71

Publisher

Elsevier

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