Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii

Document Type

Article

Publication Date

1-1-2010

Abstract

A new bisindole alkaloid, bisleuconothine A(1) consisting of an eburnane-aspidosperma type skeleton, was isolated from the bark of Leuconotis griffithii. The structure including absolute stereochemistry was elucidated on the basis of 2D NMR data and X-ray analysis. Bisleuconothine A(1) showed cell growth inhibitory activity against various human cancer cell lines. (C) 2010 Elsevier Ltd. All rights reserved.

Publication Title

Bioorganic & Medicinal Chemistry Letters

Volume

20

Issue

6

Publisher

Elsevier

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