Comparative analyses of IGA1 binding lectins from seeds of 6 distinct clones of artocarpus-integer
Document Type
Article
Publication Date
1-1-1993
Abstract
Purified lectins from seeds of six distinct clones of Artocarpus integer (lectin C) were shown to be structurally and functionally similar. All lectins comprised of two types of non-covalently-linked subunits with apparent M(r) of 13,300 and 16,000. The lectins appeared to interact with several human serum proteins, with the predominance of the IgA1 and C1 inhibitor molecules. Interaction was not detected with IgA2, IgD, IgG and IgM. The lectin Cs were also shown to precipitate monkey, sheep, rabbit, cat, hamster, rat and guinea-pig serum. Due to their uniform properties, lectin C may provide better alternative to the Artocarpus heterophyllus lectin, jacalin, for use in future investigations.
Keywords
Molecular Medicine, IGA1 Binding Lectins
Divisions
fac_med
Publication Title
Biochemistry and Molecular Biology International
Volume
29
Issue
1
Additional Information
Department of Molecular Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA