Helicobacter pylori and peptic ulcer disease--a causal link
Document Type
Article
Publication Date
6-1-1997
Abstract
The link between Helicobacter. pylori and peptic ulcer disease in 1997 is an irrefutable one. The association between infection and ulcerogenesis has been shown to be biologically plausible with induction of epithelial inflammation and cell damage and its effect on gastrin/acid homeostasis. The association of H. pylori infection and peptic ulcer disease is a close and consistent one. There is ample evidence indicating that H. pylori eradication results in virtual abolition of ulcer relapse. Several studies have demonstrated that eradication of H. pylori results in ulcer healing and there is evidence showing a temporal relationship between infection and development of peptic ulcer disease.
Keywords
Gastric Acid/secretion, Helicobacter Infections/complications, Helicobacter Infections/drug therapy
Divisions
fac_med
Publication Title
Medical Journal of Malaysia
Volume
52
Issue
2
Publisher
Malaysian Medical Association
Additional Information
Department of Medicine, University of Malaya