An immunohistochemical study of the lining epithelium of odontogenic keratocyst.

C.H. Siar
K.H. Ng

Document Type

Article

Publication Date

9-1-1995

Abstract

The lining epithelium of 15 cases of odontogenic keratocyst (OKC) was evaluated immunohistochemically. The peroxidase-antiperoxidase technique was applied to study the distribution of polyclonal keratin and S-100 protein while the indirect method was used to examine monoclonal vimentin and desmin reactivity. Consistent positive keratin staining was revealed in the lining epithelium of all 15 OKCs with additional intense staining in the stratum corneum. None of the cases showed vimentin or desmin reactivity within the lining epithelium elements. One of the 15 cysts studied showed positive S-100 protein staining in the nuclei of the lining epithelial cells. The pertinent literature on the immunophenotyping of the lining epithelium of OKC is reviewed.

Keywords

Aged, Cell Nucleus/ultrastructure

Divisions

OralPathologyOralMedicinePeriodontology

Publication Title

The Journal of Nihon University School of Dentistry

Volume

37

Issue

3

Additional Information

Department of Oral Pathology, Oral Medicine and Periodontology, Faculty of Dentistry, University of Malaya, Malaysia

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