Analysis of Salmonella typhi isolates from Southeast Asia by pulsed-field gel electrophoresis.
Document Type
Article
Publication Date
7-1-1995
Abstract
Pulsed-field gel electrophoresis (PFGE) revealed that multiple genetic variants of Salmonella typhi are simultaneously present in Southeast Asia and are associated with sporadic cases of typhoid fever and occasional outbreaks. Comparative analysis of PFGE patterns also suggested that considerable genetic diversity exists among S. typhi strains and that some PFGE patterns are shared between isolates obtained from Malaysia, Indonesia, and Thailand, implying movement of these strains within these regions of Southeast Asia, where they are endemic.
Keywords
Asia, Southeastern/epidemiology, DNA Restriction Enzymes, DNA, Bacterial/genetics, DNA, Bacterial/isolation & purification
Publication Title
Journal of Clinical Microbiology
Volume
33
Issue
7
Publisher
American Society for Microbiology
Additional Information
Centre for Foundation Studies in Science, University of Malaya