A scoping review of systematic reviews on artificial intelligence in orthopaedics

Document Type

Review

Publication Date

1-1-2026

Abstract

Background: Artificial intelligence (AI) has rapidly gained momentum in the field of orthopaedics, with an increasing number of systematic reviews and meta-analyses providing synthesised evidence. However, most studies have focused on individual subspecialties or specific applications, and a comprehensive overview across the discipline is lacking. Aim: The aim of this study is to chart publication trends and geographical distribution, classify clinical and anatomical focus, and map AI methodologies and applications in orthopaedic settings, thereby highlighting research opportunities in underexplored areas. Methods: We conducted a scoping review of freely accessible systematic reviews with and without meta-analysis across PubMed, Web of Science and Scopus databases from year 2015 up to July 2025 that evaluated the use of AI in orthopaedics. Data were extracted on publication characteristics, geographical origin, orthopaedic subspecialty focus, anatomical region, AI methodologies, data modalities, and application types. The methodological quality of the included reviews was appraised using the A Measurement Tool to Assess Systematic Reviews-2 (AMSTAR-2). Descriptive trends were summarised, and associations between variables were analysed using R software. Results: We identified 183 eligible systematic reviews published in the last 10 years, with an exponential increase in publications over the past 5 years. Most reviews concentrated on fractures, arthroplasty, and surgery-related studies, particularly in the spine, knee, and hip. Imaging datasets predominated, with deep learning most frequently applied to radiological tasks, while machine learning methods were more common in structured clinical data applications. Notable gaps remain in underrepresented anatomical regions and in underexplored applications such as prescriptive modelling. Conclusion: Our review highlights that while there is rapid growth in AI research across orthopaedics, certain clinical domains remain underexplored. These gaps represent opportunities for future work to align AI methods with clinical needs. By addressing these areas, AI has the potential to effectively support orthopaedic care and improve patient outcomes.

Publication Title

Journal of Orthopaedic Surgery

ISSN

10225536

DOI

10.1177/10225536261424033

Volume

34

Issue

1

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