Effect of temperature on the characteristics of beta-tricalcium phosphate for use as bone substitute material
Document Type
Article
Publication Date
4-1-2022
Abstract
Beta tricalcium phosphate (β-TCP) has received great attention mainly because of its excellent biodegradability. However, synthesis of single phase β-TCP with controlled properties without affecting the biocompatibility of the ceramic is a challenge. The aim of this research was to synthesize bioresrobable and osteoconductive β-TCP for use as a bone substitute material and to evaluate the mechanical properties of the ceramic. In this work, a two-step heat treatment process was adopted. Initially, the material was heat-treated at 700 °C, and subsequently sintered at different temperatures of 1000, 1100 and 1200 °C. It was revealed that the stability of the β-TCP phase was disrupted when sintered at 1200 oC with some formation of a-TCP phase. The diametral tensile strength of phasepure β-TCP sample was found to be about 4.06 MPa and was found to decline in the presence of α-TCP phase. Biological cell study showed that the β-TCP sample is excellent as a substrate for cell attachment, proliferation, differentiation, and mineralization, thus demonstrating excellent biocompatibility. This study showed that the β-TCP exhibited great potential for use as bone substitute materials. © School of Engineering, Taylor's University.
Keywords
Bone substitute, Calcium phosphate, Direct sintering, Tricalcium phosphate
Divisions
mechanical
Funders
Hanoi University of Science and Technology (HUST) [Grant No: T2018-TT-206]
Publication Title
Journal of Engineering Science and Technology
Volume
17
Issue
2
Publisher
Taylor's University