Small open reading frames in plant research: From prediction to functional characterization
Document Type
Article
Publication Date
3-1-2022
Abstract
Gene prediction is a laborious and time-consuming task. The advancement of sequencing technologies and bioinformatics tools, coupled with accelerated rate of ribosome profiling and mass spectrometry development, have made identification of small open reading frames (sORFs) (< 100 codons) in various plant genomes possible. The past 50 years have seen sORFs being isolated from many organisms. However, to date, a comprehensive sORF annotation pipeline is as yet unavailable, hence, addressed in our review. Here, we also provide current information on classification and functions of plant sORFs and their potential applications in crop improvement programs.
Keywords
Small open reading frame, Small peptide, sORFs, SEP, Hormone-like peptides
Divisions
InstituteofBiologicalSciences,cebar
Funders
Ministry of Higher Education, Malaysia, under the Fundamental Research Grant Scheme (FRGS) [Grant No: FRGS/1/2019/STG05/UM/02/3]
Publication Title
3 Biotech
Volume
12
Issue
3
Publisher
Springer Heidelberg
Publisher Location
TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY