Application of heat-killed probiotics in aquaculture

Document Type

Article

Publication Date

2-15-2022

Abstract

Probiotics confer health benefits to aquatic animals, although the use of live probiotics could negatively impact the aquaculture environment. Thus, heat-killed probiotics are an alternative choice that could equally improve growth performance and disease resistance of farmed fish and shellfish. This review summarised current understanding of heat-killed probiotics in aquaculture, including their sources, safety and effectiveness, as well as method of application, dosages, and duration of usage. Moreover, the beneficial effects of heat-killed probiotics on the intestinal structure and barrier function, feed utilisation and growth performance, tolerance to stress, protection against pathogens, and regulation of host immunity in aquatic animals are discussed. Additionally, we proposed future research directions on the application of heat-killed probiotics in aquaculture.

Keywords

Aquaculture, Heat-killed probiotic, Growth, Disease resistance, Stress resistance, Immune response

Divisions

InstituteofBiologicalSciences

Funders

National Natural Science Foundation of China (NSFC) [Grant No: 41876152 & 31850410487 & 31802341],STU Sci-entific Research Foundation for Talents [Grant No: NTF21027],Guangdong Pro-vincial Project of Science and Technology [Grant No: 2017B020204003],Guangdong Provincial Special Fund for Modern Agriculture Industry Technology Innovation Teams [Grant No: 2019KJ141]

Publication Title

Aquaculture

Volume

548

Issue

2

Publisher

Elsevier

Publisher Location

RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS

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