Determination of three endocrine disruptors in water samples by ultrasound-assisted salt-induced liquid-liquid microextraction (UA-SI-LLME) and high-performance liquid chromatography - diode array detection (HPLC-DAD)
Document Type
Article
Publication Date
1-2-2022
Abstract
Endocrine-disrupting compounds are routinely detected in environmental water. In this study, a simple and rapid sample preparation method based on ultrasound-assisted salt-induced liquid-liquid microextraction (UA-SI-LLME) followed by high performance liquid chromatography - diode array detection (HPLC-DAD) was developed for the determination of triclosan, triclocarban and methyl-triclosan in water. Parameters that affect the extraction efficiency - such as type and mass of salt, type and volume of extraction solvent, extraction time, sample pH and sample volume - were studied. Under the optimized conditions, the method demonstrated linearity from 0.18 to 1000 mu g L-1 with coefficients of determination R-2 >= 0.9899, limits of detection from 0.05 to 0.2 mu g L-1, and good recoveries (> 70%) with relative standard deviations < 10%. The method was applied for the determination of triclosan, triclocarban, and methyl-triclosan in swimming pool, lake, and wastewater. The greenness of the method was quantified using the Analytical Eco-Scale Index.
Keywords
High-performance liquid chromatography-, Diode array detection (HPLC-DAD), Methyl-triclosan, Triclocarban, triclosan, Ultrasound-assisted salt-induced liquid-liquid microextraction (UA-SI-LLME)
Divisions
CHEMISTRY
Funders
Yayasan Universiti Teknologi PETRONAS [YUTP015LC0-211]
Publication Title
Analytical Letters
Volume
55
Issue
1
Publisher
Taylor & Francis
Publisher Location
530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA