Nitrogen doped titanium dioxide as an aesthetic antimicrobial filler in dental polymers
Document Type
Article
Publication Date
1-1-2022
Abstract
To develop an aesthetic resin composite using a nitrogen-doped titanium dioxide (NTiO2) filler that possesses antimicrobial properties against cariogenic bacteria. Methods: N-TiO2 powder was manufactured by calcining commercial TiO2 with urea. Free radical release from the N-TiO2 powder under visible light irradiation was analysed using UV-Vis spectrophotometry. The N-TiO2 powder was incorporated into a dental resin and the photocatalytic activity assessed using a dye under both visible light and dark conditions. Using XTT assay to measure the cellular metabolic activity, the antibacterial properties of the N-TiO2/resin composite discs were tested using Streptococcus mutans. Results: Doping nitrogen of TiO2 resulted in a band gap shift towards the visible light spectrum, which enabled the powder to release reactive oxygen species when exposed to visible light. When incorporated into a dental resin, the N-TiO2/resin composite still demonstrated sustained release of reactive oxygen species, maintaining its photocatalytic activity and showing an antibacterial effect towards Streptococcus mutans under visible light conditions. Significance: N-TiO2 filled resin composite shows great promise as a potential aesthetic resin based adhesive for orthodontic bonding. (C) 2021 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.
Keywords
Nitrogen doped titanium dioxide, Antimicrobial, Dental adhesive, Orthodontics
Publication Title
Dentals Materials
Volume
38
Issue
1
Publisher
Elsevier
Publisher Location
THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND