Unilateral facial and limb oedema secondary to fluoxetine in a patient with haemorrhagic stroke

Document Type

Article

Publication Date

1-1-2022

Abstract

Fluoxetine is a common selective serotonin reuptake inhibitor (SSRI) used as a pharmacological neuromodulationagent for post-stroke motor recovery and treatment for post-stroke mood disorder. Although some SSRIs are known to cause bilateral symmetrical peripheral oedema, to datethere are no reported cases of oedemacaused by fluoxetine or reported cases of a unilateral peripheral oedema. We report a case of fluoxetine-induced unilateral facial and limb oedema in a patient with haemorrhagic stroke. The peripheral oedema was noted on the hemiparetic side within 48 hours after theinitiation of fluoxetine.The medication was then tapered off over two weeks, which resulted in gradual resolution of the oedema. © 2022, Faculty of Medicine, University of Malaya. All rights reserved.

Keywords

Fluoxetine, Motor recovery, Peripheral oedema, Post-stroke, SSR

Divisions

fac_med

Publication Title

Journal of Health and Translational Medicine

Volume

25

Issue

1

Publisher

Faculty of Medicine, University of Malaya

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