Synthesis of polycaprolactone using novel crude lipase: Parameter optimization
Document Type
Conference Item
Publication Date
1-1-2022
Abstract
Polycaprolactone was synthesized using ring opening polymerization process by utilizing a novel lipase enzyme from Aspergillus niger sp. D-optimal design in DoE was used to optimize the reaction parameters for the synthesis of polycaprolactone. The variables selected were temperature (30–70 °C), time (30–150 min), mixing speed (100–500 rpm) and enzyme volume (5–9 mL). The response variable chosen is the number average molecular weight, Mn. Experimental results obtained was used to explain the interactions between parameters and responses were analyzed and validated. The result shows a good agreement with a minimum error between the actual and predicted values as the error is only 2.35. © 2022, Springer Nature Switzerland AG.
Keywords
Lipase, Polycaprolactone, Polymerization
Divisions
sch_che,InstituteofBiologicalSciences
Publication Title
IFMBE Proceedings
Volume
86
Publisher
Springer Science and Business Media Deutschland GmbH
Event Title
6th Kuala Lumpur International Conference on Biomedical Engineering, BioMed 2021
Event Location
Virtual, Online
Event Dates
28-29 July 2021
Event Type
conference