Subacute myelopathy following intrathecal chemotherapy administration
Document Type
Article
Publication Date
1-1-2022
Abstract
Methotrexate and cytarabine are intrathecal chemotherapy agents for acute lymphoblastic leukaemia. We report a case of a paediatric patient with late onset CNS relapse of Pre-B acute lymphoblastic leukaemia who developed chemotherapy-induced myelopathy secondary to triple intrathecal chemotherapy (TIT) with its imaging findings. Imaging plays a role in localising abnormality within the spinal cord for diagnosis and aids clinicians to prevent further axonal damage by stopping the causative chemotherapeutic agents. © 2022, Brunei International Medical Journal. All rights reserved.
Keywords
Acute lymphoblastic leukemia, Chemotherapy-induced, Intrathecal, Magnetic resonance imaging, Myelopathy
Divisions
biomed
Publication Title
Brunei International Medical Journal
Volume
2022
Issue
18
Publisher
Ministry of Health