Subacute myelopathy following intrathecal chemotherapy administration

Authors

• N Ab Mumin
• MT Ramli Hamid
• Kartini RahmatFollow
• V. Jawin
• Norlisah Mohd RamliFollow

Document Type

Article

Publication Date

1-1-2022

Abstract

Methotrexate and cytarabine are intrathecal chemotherapy agents for acute lymphoblastic leukaemia. We report a case of a paediatric patient with late onset CNS relapse of Pre-B acute lymphoblastic leukaemia who developed chemotherapy-induced myelopathy secondary to triple intrathecal chemotherapy (TIT) with its imaging findings. Imaging plays a role in localising abnormality within the spinal cord for diagnosis and aids clinicians to prevent further axonal damage by stopping the causative chemotherapeutic agents. © 2022, Brunei International Medical Journal. All rights reserved.

Keywords

Acute lymphoblastic leukemia, Chemotherapy-induced, Intrathecal, Magnetic resonance imaging, Myelopathy

Publication Title

Brunei International Medical Journal

Recommended Citation

Mumin, N Ab; Hamid, MT Ramli; Rahmat, Kartini; Jawin, V.; and Mohd Ramli, Norlisah, "Subacute myelopathy following intrathecal chemotherapy administration" (2022). Research Publications (2021 to 2025). 8676.
https://knova.um.edu.my/research_publications_2021_2025/8676

Divisions

biomed

Volume

2022

Issue

18

Publisher

Ministry of Health