Multimodal linear endobronchial ultrasound guided mediastinal lymph node biopsy in the diagnosis of isolated mediastinal lymphadenopathy
Document Type
Article
Publication Date
1-1-2022
Abstract
Isolated mediastinal lymphadenopathy represents a common diagnostic dilemma whereby morphological analysis of tissue specimens are frequently needed to ascertain the diagnosis. Cryobiopsy by linear endobronchial ultrasound (EBUS) guidance had recently been described in literature. We described a multimodality biopsy approach of a case of isolated tuberculous mediastinal lymphadenitis in which we employed the 22-gauge transbronchial aspiration needle, mini-forceps and a flexible cryoprobe sequentially. We aim to highlight the novel technique of linear EBUS guided cryobiopsy in acquiring superior histological specimen from mediastinal lymphadenopathy for diagnosis purposes. We also compared the histopathological quality of the specimens acquired from these three different biopsy modalities. © The Author(s) 2022.
Keywords
Anesthetic agent, Ethambutol plus isoniazid plus pyrazinamide plus rifampicin, Acid fast bacterium, Adolescent, Anesthesia, Aortopulmonary septal defect, Article, Bronchoscopy, Case report, Clinical article, Computer assisted tomography, Cryobiopsy, Dry cough, Endobronchial ultrasonography, Exertional dyspnea, Hepatosplenomegaly, Histopathology, Human, Human tissue, Lymph node biopsy, Lymphadenopathy, Male, Mediastinal lymphadenopathy, Mediastinum lymph node, Morphology, Multimodal imaging, Mycobacterium tuberculosis, Physical examination, Pneumomediastinum, Pneumothorax, Transbronchial aspiration, Tuberculous lymphadenitis
Divisions
fac_med
Funders
None
Publication Title
Proceedings of Singapore Healthcare
Volume
31
Publisher
SAGE Publications