Improving anthelmintic treatment for schistosomiasis and soil-transmitted helminthiases through sharing and reuse of individual participant data
Document Type
Article
Publication Date
1-1-2022
Abstract
The Infectious Diseases Data Observatory (IDDO, https://www.iddo.org) has launched a clinical data platform for the collation, curation, standardisation and reuse of individual participant data (IPD) on treatments for two of the most globally important neglected tropical diseases (NTDs), schistosomiasis (SCH) and soil-transmitted helminthiases (STHs). This initiative aims to harness the power of data-sharing by facilitating collaborative joint analyses of pooled datasets to generate robust evidence on the efficacy and safety of anthelminthic treatment regimens. A crucial component of this endeavour has been the development of a Research Agenda to promote engagement with the SCH and STH research and disease control communities by highlighting key questions that could be tackled using data shared through the IDDO platform. Here, we give a contextual overview of the priority research themes articulated in the Research Agenda-a 'living' document hosted on the IDDO website-and describe the three-stage consultation process behind its development. We also discuss the sustainability and future directions of the platform, emphasising throughout the power and promise of ethical and equitable sharing and reuse of clinical data to support the elimination of NTDs. © 2022 Walker M et al.
Keywords
Anthelmintic, Data reuse, Data sharing, Neglected tropical diseases, Schistosomiasis, Soil-transmitted helminthiasis, Treatment
Divisions
Parasit
Funders
Firoz Lalji Institute for Africa,World Health Organization,University of Georgia,Ministry of Health,London School of Economics and Political Science
Publication Title
Wellcome Open Research
Volume
7
Issue
2
Publisher
F1000 Research Ltd