Paper-based polymeric ionic liquid for thin film micro extraction of sulfonamides in environmental water samples prior to HPLC-DAD analysis
Document Type
Article
Publication Date
12-1-2021
Abstract
Paper-based polymeric ionic liquid (p-Poly-(MMA-IL)) was successfully developed by grafting the polymeric ionic liquid on the surface of commercial filter paper by using dipping method, presenting a new cost-effective film. The newly developed p-Poly-(MMA-IL) was then applied as a paper-based thin film microextraction (p-TFME) to extract four representative sulfonamides (SAs) drugs, which were sulfadiazine, sulfachloropyridazine, sulfamethoxazole, and sulfadimethoxine in environmental water samples. Besides, p-Poly-(MMA-IL) was suc-cessfully characterised by FTIR, FESEM, and XRD techniques and underwent significant parameters optimisation, which affected the extraction efficiency. Under optimal conditions, the proposed method (p-Poly-(MMA-IL)-TFME) was evaluated and applied to analyse SAs in environmental water samples by using a high-performance liquid chromatography-diode array detector (HPLC-DAD). The validation method showed that a good linearity (0.50 mu g L-1 -500 mu g L-1) was noted (R-2 > 0.999, n = 3). Detection and quantification limits were within 0.14 mu g L-1 - 0.52 mu g L-1 and 0.41 - 1.57 mu g L-1, respectively, the preconcentraction factors were > 14.95, and the matrix effect was less than 2.64%, an acceptable percentage for real samples analysis. The extraction recoveries of environmental water samples were ranged from 90.4% to 109.9% with a relative standard deviation (RSD) of less than 9.8%. The newly developed paper-based polymeric ionic liquid (p-Poly-(MMA-IL) for analysis of SAs under the p-TFME procedure was successfully achieved with limited sample volume and organic solvent, fast extrac-tion, and practicable in the daily analysis.
Keywords
Paper-based materials, Polymeric ionic liquid, Sulfonamides, Thin film microextraction, High-performance liquid chromatography, Environmental water samples
Divisions
CHEMISTRY
Funders
Universiti Malaya [GPF058B-2018],FRGS grant [FP071-2018A],University Malaya Centre for Ionic Liquids (UMCIL)
Publication Title
Microchemical Journal
Volume
171
Publisher
Elsevier
Publisher Location
RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS