Prevalence of dark without pressure and angioid streaks in sickle cell disease
Document Type
Article
Publication Date
11-1-2021
Abstract
BACKGROUND AND OBJECTIVES: To investigate the prevalence of areas of dark without pressure (DWOP) and angioid streaks (AS) in patients with sickle cell disease (SCD). PATIENTS AND METHODS: This was a consecutive series of 77 adults with SCD. RESULTS: DWOP appeared as multiple patches in 35 of the affected eyes and as a single lesion in 3 eyes. OCT finding demonstrated the ellipsoid layer was hyporeflective in DWOP. AS were identified in six cases (3.9%) and were bilateral in five cases. The prevalence of AS was higher with increasing age, being 67% in the patients older than age 45 years. CONCLUSION: The prevalence of DWOP in adults with SCD is 25% in this study, which is higher than previously reported, and the prevalence of AS is around 4%, which is midway between prior estimates. Recognition of the clinical examination and imaging features of DWOP reduce the need for additional investigation.
Keywords
Dark without pressure, Angioid streaks, Sickle cell disease
Divisions
ophthalmplogy
Publication Title
Ophthalmic Surgery Lasers & Imaging Retina
Volume
52
Issue
11
Publisher
Slack Inc
Publisher Location
6900 GROVE RD, THOROFARE, NJ 08086 USA