Shear wave elastography: A review on the confounding factors and their potential mitigation in detecting chronic kidney disease
Document Type
Article
Publication Date
8-1-2021
Abstract
Early detection of chronic kidney disease is important to prevent progression of irreversible kidney damage, reducing the need for renal transplantation. Shear wave elastography is ideal as a quantitative imaging modality to detect chronic kidney disease because of its non-invasive nature, low cost and portability, making it highly accessible. However, the complexity of the kidney architecture and its tissue properties give rise to various confounding factors that affect the reliability of shear wave elastography in detecting chronic kidney disease, thus limiting its application to clinical trials. The objective of this review is to highlight the confounding factors presented by the complex properties of the kidney, in addition to outlining potential mitigation strategies, along with the prospect of increasing the versatility and reliability of shear wave elastography in detecting chronic kidney disease. (C) 2021 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
Keywords
Shear wave elastography, Chronic kidney disease, Ultrasound, Medical imaging, Viscoelasticity, Anisotropy, Hemodynamics, Fibrosis, Acoustic radiation force, Stiffness
Divisions
fac_med,biomed
Publication Title
Ultrasound in Medicine and Biology
Volume
47
Issue
8
Publisher
Elsevier Science Inc
Publisher Location
STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA