Sudden death in a case of triple-vessel, non-atherosclerotic, diffuse ectasia and aneurysmal dilatations of the coronary arteries: An autopsy report

Document Type

Article

Publication Date

3-1-2025

Abstract

Aneurysmal Coronary Artery Disease (ACAD) can occur as localized dilations of a segment of one or more coronary arteries or diffuse ectasia-type dilatations of one or more coronaries. Atherosclerosis remains the most common cause of these aneurysms, with Kawasaki Disease being implicated in the Asian population. We present a case of a 62-year-old Asian woman who dies suddenly with no prior symptoms. and underwent an autopsy. Her heart showed diffuse aneurysmal dilatations of the epicardial coronary arteries, with a giant saccular aneurysm of the left main coronary artery. Histopathology revealed medial degeneration of the aneurysmal wall with no evidence of atheroma or vasculitis. Following a review of the pathological causes of coronary aneurysms, it is likely that the cause of such diffuse dilatations of the coronaries could be previous vasculitis such as Kawasaki disease.

Keywords

Coronary artery aneurysm, Aneurysmal coronary artery disease, Coronary artery ectasia, Giant aneurysm, Kawasaki disease

Divisions

ummc

Publication Title

Cardiovascular Pathology

Volume

75

Publisher

Elsevier

Publisher Location

STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA

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