Carbon nanomaterials as electrochemical sensors for theophylline: A review
Document Type
Article
Publication Date
9-1-2024
Abstract
Theophylline (TP) is a methylxanthine derivative, which serves as a valuable compound in treating respiratory disorders and acts as a bronchodilator agent. However, TP has a limited therapeutic range (20-100 mu mol L-1), demanding precise monitoring to prevent potential drug toxicity even with slight level fluctuations during treatment. Thus, to overcome this limitation, electrochemical methods have been extensively used due to their efficacy in achieving sensitivity, selectivity, and accuracy. In the context of electrochemical sensors, nanocarbon-based materials have gained widespread recognition for their extensive applications. Therefore, this review aims to explore the latest advancements in carbon-based electrodes particularly used for the precise determination of TP through electrochemical methods. The results are expected to provide insights into the profound significance of the methods in enhancing the accuracy and sensitivity for the detection of TP. Recent progress in the utilization of nanocarbon-based materials, such as graphene, nanodiamond, and CNTs, is discussed regarding their enhanced performance in electrochemical sensors for theophylline.
Keywords
Nanocomposite, Electroanalytical application, Gold nanoparticle
Divisions
CHEMISTRY,nanocat
Funders
Universitas Airlangga [Grant No: 191/UN3 LPPM/PT.01.03/2024],Universitas Airlangga by International Report Consortium
Publication Title
RSC Advances
Volume
14
Issue
39
Publisher
Royal Society of Chemistry
Publisher Location
THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND