Experience in managing glaucoma filtration surgery complications with oral doxycycline: A case series
Document Type
Article
Publication Date
7-1-2022
Abstract
Purpose: To report the clinical profile and effectiveness of oral doxycycline as a non-invasive treatment for glaucoma filtering surgery complications. Method: Prospective case series. Results: Doxycycline is widely used in treating corneal melts, ocular surface diseases, meibomian gland disease, recurrent epithelial cell erosion, rosacea, and keratitis sicca. This prospective case series highlights the successful treatment of five patients with leaking blebs and conjunctiva erosion from glaucoma filtration surgery with the use of oral doxycycline. There was no adverse event reported in our cases. Conclusions: This study suggests that oral doxycycline may be a feasible non-surgical treatment modality due to its ability to inhibit collagenolysis, restore the Meibomian gland function, thereby stopping breakdown and promote conjunctival tissue healing.
Keywords
Doxycycline, Glaucoma filtration surgery, Hypotony, Bleb leaks, Complication
Divisions
ophthalmplogy
Funders
None
Publication Title
European Journal of Ophthalmology
Volume
32
Issue
4
Publisher
SAGE Publications
Publisher Location
1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND