Recent advancements in smart MXene quantum dot-based nanosystems for immunomodulatory and effective cancer treatment
Document Type
Article
Publication Date
6-1-2024
Abstract
MXene quantum dots (MQDs) are a novel generation of smart nanosystems for various biomedical and pharmaceutical applications, such as biological imaging/sensing, tissue engineering, cancer diagnostics/therapy, analytical biochemistry, and drug/gene delivery, owing to their specific instinct characteristics and biocompatibility. However, there are several challenges related to their histopathology, long-term toxicity, biodegradability, photoluminescence (especially in clinical studies), and biodistribution properties, which must be carefully assessed. In addition to developing highly scalable and optimized synthesis methods for MQD-based nanosystems, more advanced smart MXene-based platforms and their hybrid nanocomposites must be developed to address the uprising requirements. A smart nanosystem based on MQDs with improved properties requires advanced functionalization strategies, improved synthesis methods, and cytotoxicity/biosafety evaluations. The current review article highlighted recent developments in the immunomodulatory cancer applications of MQDs, focusing on current trends and future perspectives.
Keywords
MXene quantum dots, Smart quantum dots, Immune system, Cancer treatment, Nanosystems
Divisions
nanotechnology
Funders
National Science and Technology Council, Taiwan (NSTC 111-2223-E-011-002-MY3) ; (NSTC 111-2628-E-011-002-MY2) ; (NSTC 113-2927-I-011-504),Ministry of Education, Taiwan ("Sustainable Electrochemical Energy Development Center" (SEED) project),National Taiwan University of Science and Technology,Prince Sattam bin Abdulaziz University (PSAU/2023/R/1444)
Publication Title
Materials Today Chemistry
Volume
38
Publisher
Elsevier
Publisher Location
125 London Wall, London, ENGLAND