Secondary metabolites in topical infectious diseases and nanomedicine applications
Document Type
Article
Publication Date
5-1-2024
Abstract
Topical infection affects nearly one-third of the world's population; it may result from poor sanitation, hygienic conditions and crowded living and working conditions that accelerate the spread of topical infectious diseases. The problems associated with the anti-infective agents are drug resistance and long-term therapy. Secondary metabolites are obtained from plants, microorganisms and animals, but they are metabolized inside the human body. The integration of nanotechnology into secondary metabolites is gaining attention due to their interaction at the subatomic and skin-tissue levels. Hydrogel, liposomes, lipidic nanoparticles, polymeric nanoparticles and metallic nanoparticles are the most suitable carriers for secondary metabolite delivery. Therefore, the present review article extensively discusses the topical applications of nanomedicines for the effective delivery of secondary metabolites.
Keywords
bacteria, fungi, nanomedicine, nanotoxicology, secondary metabolites, skin, topical infection, virus
Divisions
fac_med
Funders
Deanship for Research & Innovation, Ministry of Education, Saudi Arabia (IFP22UQU4310387DSR158)
Publication Title
Nanomedicine
Volume
19
Issue
13
Publisher
Taylor & Francis
Publisher Location
2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND