Three-dimensional carbon interdigitated ring array nanofibers for electrochemical detection of dopamine neurotransmitter
Document Type
Article
Publication Date
3-1-2024
Abstract
Dopamine (DA) neurotransmitter is a prominent component of the central nervous system and its deficiency contributes to several diseases, such as Parkinson's disease and schizophrenia, which significantly influence the quality of life of affected individuals. This paper introduces a circular interdigitated ring electrode, the three-dimensional carbon interdigitated ring array nanofibers (3D C-IDRA NFs), for the detection of DA using amperometric detection. The study utilized cyclic voltammetry and chronoamperometry to investigate DA. The integration of carbon nanofibers (CNFs) with 3D C-IDRA demonstrated enhanced surface area, increased current peak, and superior performance compared to the standalone 3D C-IDRA electrode, as evidenced by a redox amplification factor of 2.94 and a collection efficiency of 81.1%. The results highlight that integrating CNFs with 3D C-IDRA improves the electrochemical performance in detecting DA neurotransmitter. Thus, this discovery elucidates the advantageous potential of the 3D C-IDRA NF electrode in a wide range of applications.
Keywords
interdigitated ring array, carbon MEMS, carbon nanofibers, cyclic voltammetry, electrochemical analysis, dopamine
Divisions
fac_eng,biomedengine
Funders
Ministry of Energy, Science, Technology, Environment and Climate Change (MESTECC), Malaysia (MOSTI002B-2022TED1),Ministry of Higher Education & Scientific Research (MHESR),Universiti Malaya (TU003-2019); (IIRG007A-19HWB)
Publication Title
Journal of Micromechanics and Microengineering
Volume
34
Issue
3
Publisher
IOP Publishing
Publisher Location
TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND