Utility and applicability of rapid diagnostic testing in antimicrobial stewardship in the asia-pacific region: a delphi consensus

Document Type

Article

Publication Date

6-1-2022

Abstract

A group of experienced practitioners provide 10 consensus statements for guiding the use of rapid diagnostic tests in antimicrobial stewardship in the Asia-Pacific region, including definitions, types, optimal deployment, measuring effectiveness, and overcoming key challenges. Rapid diagnostic tests (RDTs) facilitate fast and accurate identification of infectious disease microorganisms and are a valuable component of multimodal antimicrobial stewardship (AMS) programs but are currently underutilized in the Asia-Pacific region. An experienced group of infectious diseases clinicians, clinical microbiologists, and a clinical pharmacist used a modified Delphi consensus approach to construct 10 statements, aiming to optimize the utility and applicability of infection-related RDTs for AMS in the Asia-Pacific region. They provide guidance on definition, types, optimal deployment, measuring effectiveness, and overcoming key challenges. The Grading of Recommendations Assessment, Development, and Evaluation system was applied to indicate the strength of the recommendation and the quality of the underlying evidence. Given the diversity of the Asia-Pacific region, the trajectory of RDT development will vary widely; the collection of local data should be prioritized to allow realization and optimization of the full benefits of RDTs in AMS.

Keywords

Asia-Pacific region, Antimicrobial stewardship, Point-of-care testing, Rapid diagnostic testing

Divisions

fac_med

Funders

healthcare team from Weber Shandwick Hong Kong - bioMerieux

Publication Title

Clinical Infectious Diseases

Volume

74

Issue

11

Publisher

Oxford University Press

Publisher Location

JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA

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