Green synthesis of antibacterial nanocomposite of silver nanoparticle-doped hydroxyapatite utilizing Curcuma longa leaf extract and land snail (Achatina fulica) shell waste
Document Type
Article
Publication Date
6-1-2022
Abstract
Preparation of green synthesized silver nanoparticle (AgNPs)-doped hydroxyapatite (Ag/HA) utilizing Curcuma longa leaf extract and land snail (Achatina fulica) shell waste was performed. Physicochemical characteristics and antibacterial activity of Ag/HA composite as a function of Ag content was studied. Instrumental analysis such as XRD, SEM-EDX, TEM, and XPS were employed to characterize the nanocomposites. The physicochemical study revealed the maintained porous structure of HA after Ag immobilization, and from TEM analyses, it was found that the distributed spherical particles are associated with the dispersed Ag and have a particle diameter of around 5-25 nm. Antibacterial activity of the nanocomposite was evaluated against Escherichia coli, Staphylococcus aureus, Kliebsiella pneumonia, and Streptococcus pyogenes. The results showed that the varied Ag content (1.0; 1.6; and 2.4% wt) influenced the nanoparticle distribution in the nanocomposite and enhanced the antibacterial feature.
Keywords
Hydroxyapatite, Silver nanoparticles, Antibacterial nanocomposite
Divisions
nanocat
Funders
Universitas Islam Indonesia (Grant No: 001/Dir/DPPM/70/Pen)
Publication Title
Journal of Functional Biomaterials
Volume
13
Issue
2
Publisher
MDPI
Publisher Location
ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND