Exploring graphene and its potential in delivery of drugs and biomolecules
Document Type
Article
Publication Date
6-1-2023
Abstract
Graphene hailed as the ``wonder material'' of the 21st century has achieved widespread advancements in various disciplines such as applied science and medical science. Due to its unique properties such as selectivity, greater medicament capacity, chemo-sensitization, and comfort of functionalization, extraordinary energy has been focused to explore its biomedical operation, particularly in chemotherapy, and in the development advanced delivery systems for drugs, biomolecules, and genes in the previous era. Graphene oxide, which may be coupled covalently or non-covalently with both hydrophilic and hydrophobic molecules, has also emerged as a key nano -vector because of its well-defined physicochemical features.Previously, several studies have been demonstrated that the functionalized form of graphene exhibits greater biocompatibility and could be a promising medium for the development of a novel transport mechanism, although few concerns remain their in vivo properties. This review focuses on graphene and its derivatives and their function in nanomedicine, in particularly the transport of drugs and biomolecules, as well as in the future trends and challenges associated with graphene-based materials.
Keywords
Graphene, Wonder material, Advanced delivery system, Biomolecules, Nanomedicine
Divisions
nanotechnology
Publication Title
Journal of Drug Delivery Science and Technology
Volume
84
Publisher
Elsevier
Publisher Location
RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS