Recent development of nanomaterials for transdermal drug delivery
Document Type
Article
Publication Date
4-1-2023
Abstract
Nano-engineered medical products first appeared in the last decade. The current research in this area focuses on developing safe drugs with minimal adverse effects associated with the pharmacologically active cargo. Transdermal drug delivery, an alternative to oral administration, offers patient convenience, avoids first-pass hepatic metabolism, provides local targeting, and reduces effective drug toxicities. Nanomaterials provide alternatives to conventional transdermal drug delivery including patches, gels, sprays, and lotions, but it is crucial to understand the transport mechanisms involved. This article reviews the recent research trends in transdermal drug delivery and emphasizes the mechanisms and nano-formulations currently in vogue.
Keywords
Nanomaterials, Transdermal drug delivery, Transdermal mechanisms
Divisions
medbio
Funders
Malaysian Ministry of Higher Education (MOHE) [Grant No: FRGS/1/2021/SKK06/TAYLOR/02/2],Universiti Malaya [Grant No: GPF004A-2020]
Publication Title
Biomedicines
Volume
11
Issue
4
Publisher
MDPI
Publisher Location
ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND