Alcohol consumption patterns and risk of early-onset vasomotor symptoms in premenopausal women
Document Type
Article
Publication Date
6-1-2022
Abstract
The role of alcohol consumption in the risk of vasomotor symptoms (VMS), the most cardinal climacteric symptoms, is not well established. We examined their relationship with early-onset VMS among premenopausal women. Moderately-to-severely bothersome VMS, the primary outcome, was assessed using the Korean version of the Menopause-Specific Quality of Life questionnaire. The alcohol consumption categories included lifetime abstainer, former drinker, or current drinker, categorized as light, moderate, heavy, and very heavy. Compared with the lifetime-abstinence (reference), the multivariable-adjusted odds ratio (95% CIs) for prevalent VMS in alcohol consumption of <10, 10-19, 20-39, and >= 40 g/day were 1.42 (1.02-1.99), 1.99 (1.27-3.12), 2.06 (1.19-3.57), and 3.52 (1.72-7.20), respectively (p trend <0.01). Compared with the lifetime-abstinence, the multivariable-adjusted hazard ratios (95% CIs) for incident bothersome VMS among average alcohol consumption of <10, 10-19, 20-39, and >= 40 g/day were 1.10 (0.85-1.41), 1.03 (0.70-1.51), 1.72 (1.06-2.78), and 2.22 (1.16-4.23), respectively (p trend = 0.02). Increased alcohol consumption positively and consistently showed a relationship with increased risk of both prevalent and incident early-onset VMS. Refraining from alcohol consumption may help prevent bothersome VMS in premenopausal women.
Keywords
Alcohol consumption, Hot flashes, Night sweats, Vasomotor symptoms, Premenopausal women
Divisions
Socialprevent
Funders
Korea Centers for Disease Control and Prevention [Grant No:2014ER630200],Korea Centers for Disease Control and Prevention [Grant No:2017ER630200],Korea Centers for Disease Control and Prevention [Grant No:2020-ER7102-00],Korea Centers for Disease Control and Prevention [Grant No:2020ER710201],Korea Centers for Disease Control and Prevention [Grant No:2020ER710202
Publication Title
Nutrients
Volume
14
Issue
11
Publisher Location
ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND