Mushroom beta-glucan and polyphenol formulations as natural immunity boosters and balancers: Nature of the application
Document Type
Article
Publication Date
3-1-2023
Abstract
Mushrooms are experiencing a kind of renaissance as a part of the contemporary human diet. These valuable organisms are more than food, they fit in perfectly as a novel market group known as nuts-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such as polyphenols are the main focus of the healthcare industry. Wellness and cosmetic companies arc increasingly using mushroom extracts rich in these ingredients. This review considers the basic molecular immunomodulatory mechanisms of action of the most commonly used mushroom dietary fibers, beta-glucans. The literature data on their bioavailability, metabolic transformations, preclinical and human clinical research, and safety are discussed. Immunomodulatory mechanisms of polyphenol ingredients are also considered. These molecules present great potential in the design of the new immunity balancer formulations according to their widespread structural diversity. Finally, we draw attention to the perspectives of modern trends in mushroom nutraceutical and cosmeceutical formulations to strengthen and balance immunity. (C) 2023 Beijing Academy of Food Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.
Keywords
Mushrooms, Beta-Glucan, Polyphenols, Immunity boosters, Superfood, Natural cosmetics
Divisions
InstituteofBiologicalSciences
Funders
Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja,451-03-68/2022-14/200051, 451-03-68/2022-14/200116,Science Fund of the Republic of Serbia,7748088
Publication Title
Food Science and Human Wellness
Volume
12
Issue
2
Publisher
KeAi Publishing Ltd
Publisher Location
16 DONGHUANGCHENGGEN NORTH ST, Building 5, Room 411, BEIJING, DONGCHENG DISTRICT 100009, PEOPLES R CHINA