Menthol and fatty acid-based hydrophobic deep eutectic solvents as media for enzyme activation
Document Type
Article
Publication Date
2-1-2023
Abstract
This research aims to provide insights into the biological efficacy of a newly formed hydrophobic deep eutectic solvent (DES). A DES based on menthol was successfully synthesized with fatty acids. The DESs' properties as enzyme activators were examined against a neat counterpart. The menthol:decanoic acid (1:1) combination showed improved thermal stability, strong catalytic activity, and reusability for up to four subsequent cycles under ideal conditions (pH 7.0, 40 degrees C for 2 h). The hydrophobic DES replaced hexane in ester synthesis, where RNL@DES5 showed better fatty acid conversion compared to neat RNL. This study demonstrated promising applications of hydrophobic DESs in non-aqueous organic reactions.
Keywords
Fatty acid, Natural deep eutectic solvents, Hydrophobic agent, Enzyme kinetics, Hydrogen-bonding
Divisions
sch_che,CHEMISTRY
Funders
Ministry of Higher Education, MoHE-Malaysia (Grant No: FRGS/1/2020/STG05/UM/02/11)
Publication Title
Processes
Volume
11
Issue
2
Publisher
MDPI
Publisher Location
ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND