Isolated cervical lymph node sarcoidosis: A diagnostic challenge of a case report
Document Type
Article
Publication Date
2-1-2023
Abstract
Background:Sarcoidosis is a granulomatous disorder involving multi-systemic organs. Patients invariably have lung involvement but some may have extrapulmonary disease. Rarely, cervical lymphadenopathy is the only sign without mediastinal or pulmonary abnormalities. Case presentation:We report a Malay male who complained of neck swelling exclusively. On imaging, multiple enlarged cervical lymph nodes deep to the sternocleidomastoid muscle were seen. An excision biopsy revealed non-caseating granulomas with epithelioid macrophages. Extensive investigations led to the diagnosis of isolated cervical lymph node sarcoidosis. Conclusions:Sarcoidosis can present as cervical lymphadenopathy alone, without mediastinal or lung disease. The presence of epithelioid granulomas on histopathology warrants the exclusion of other granulomatous diseases. Isolated cervical lymph node sarcoidosis is only diagnosed in the presence of consistent clinical and radiological findings. In this case, close monitoring for systemic sarcoidosis is important as it can manifest later in life.
Keywords
Granulomatous disease, Cervical lymphadenopathy, Sarcoidosis, Lymph node excision, Biopsy
Divisions
otorhino
Funders
None
Publication Title
European Archives of Oto-Rhino-Laryngology
Volume
280
Issue
2
Publisher
Springer Science and Business Media Deutschland GmbH
Publisher Location
ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES