Nature-inspired surface structures design for antimicrobial applications

Document Type

Article

Publication Date

1-1-2023

Abstract

Surface contamination by microorganisms such as viruses and bacteria may simultaneously aggravate the biofouling of surfaces and infection of wounds and promote cross-species transmission and the rapid evolution of microbes in emerging diseases. In addition, natural surface structures with unique anti-biofouling properties may be used as guide templates for the development of functional antimicrobial surfaces. Further, these structure-related antimicrobial surfaces can be categorized into microbicidal and anti-biofouling surfaces. This review introduces the recent advances in the development of microbicidal and anti-biofouling surfaces inspired by natural structures and discusses the related antimicrobial mechanisms, surface topography design, material application, manufacturing techniques, and antimicrobial efficiencies.

Keywords

Antimicrobial surface, Anti-bacteria, Anti-virus, Anti-biofouling, Structure, Surface topography

Divisions

fac_med

Funders

National Science and Technology Council (NSTC), Taiwan, ROC (Grant No: MOST 111-2321-B-A49-007, MOST 111-2112-M-A49-025, MOST 108-2320-B-010-019-MY3, MOST 109-2327-B-010-007, MOST 109-2327-B-016-002 & NSTC 111-2927-I-A49-004),Impact-oriented Interdisciplinary Research Grant (IIRG) from University of Malaya (Grant No: IIRG003B-19FNW),Ministry of Education, Malaysia,Establishment of Regenerative Medicine and Cell Therapy Platform of Veterans General Hospital system (Grant No: 110VACS-003),Establishment of epidemic prevention and research platform in the veterans medical system for the control of emerging infectious diseases (Grant No: 110VACS-007),Ministry of Health and Welfare (MOHW) (Grant No: MOHW108-TDU-B-211-133001 & MOHW109-TDU-B-211-114001),VGH, NTUH Joint Research Program (Grant No: VN109-16),VGH, TSGH, NDMC, AS Joint Research Program (Grant No: VTA107-V1-5-1, VTA108-V1-5-3 & VTA109-V1-4-1),AS Clinical Research Center (Grant No: IBMS-CRC109-P04)

Publication Title

International Journal of Molecular Sciences

Volume

24

Issue

2

Publisher

MDPI

Publisher Location

ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND

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