Recent advances of gamma-aminobutyric acid: Physiological and immunity function, enrichment, and metabolic pathway
Document Type
Article
Publication Date
12-22-2022
Abstract
gamma-aminobutyric acid (GABA) is a non-protein amino acid which naturally and widely occurs in animals, plants, and microorganisms. As the chief inhibitory neurotransmitter in the central nervous system of mammals, it has become a popular dietary supplement and has promising application in food industry. The current article reviews the most recent literature regarding the physiological functions, preparation methods, enrichment methods, metabolic pathways, and applications of GABA. This review sheds light on developing GABA-enriched plant varieties and food products, and provides insights for efficient production of GABA through synthetic biology approaches.
Keywords
GABA, Environmental stress, Microbial fermentation, Neurotransmitter, Anabolism, Catabolism, Biofortification breeding
Divisions
InstituteofBiologicalSciences
Funders
Shanghai Agriculture Applied Technology Development Program, China,STCSM International Science and Technology Cooperation Program (Grant No: 2022-02-08-00-12-F01137),Shanghai Sailing Program (Grant No: 18390741000),Jiangxi Provincial Natural Science Foundation (Grant No: 19YF 1443100),Shenzhen International Cooperation Research Program (Grant No: 20212BAB205037 & GJHZ201908 201642704)
Publication Title
Frontiers in Nutrition
Volume
9
Publisher
Frontiers Media SA
Publisher Location
AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND