Neuroimaging in dementia syndromes
Document Type
Article
Publication Date
12-1-2022
Abstract
Neuroimaging is essential for early diagnosis of different types of dementia. Structural imaging is recommended for patients with new-onset cognitive impairment and magnetic resonance imaging is the modality of choice. When atypical features are present, functional and molecular imaging is helpful for further characterisation of neurodegenerative changes. Accurate identification of dementia subtypes enables early initiation of specific molecular targeted therapies. This article provides an overview of the structural, biochemical and functional changes in common dementia subtypes that may be diagnosed through neuroimaging, emphasising new techniques like perfusion and functional imaging.
Keywords
Dementia, Magnetic resonance imaging (MRI), Perfusion imaging, Functional imaging, Cognitive dysfunction
Divisions
biomed,medicinedept
Funders
Universiti Malaya Postgraduate Research Fund,Universiti Malaya Research Grant Programme (Wellness) Fund (Grant No: PO076-2015B & RP052B-17HTM)
Publication Title
Neurology Asia
Volume
27
Issue
4
Publisher
ASEAN Neurological Association
Publisher Location
UNIV MALAYA MEDICAL CENTRE, NEUROLOGY LABORATORY, KUALA LUMPUR, 59100, MALAYSIA