Plasmodium knowlesi: The game changer for malaria eradication

Document Type

Article

Publication Date

5-1-2022

Abstract

Plasmodium knowlesi is a zoonotic malaria parasite that has gained increasing medical interest over the past two decades. This zoonotic parasitic infection is prevalent in Southeast Asia and causes many cases with fulminant pathology. Despite several biogeographical restrictions that limit its distribution, knowlesi malaria cases have been reported in different parts of the world due to travelling and tourism activities. Here, breakthroughs and key information generated from recent (over the past five years, but not limited to) studies conducted on P. knowlesi were reviewed, and the knowledge gap in various research aspects that need to be filled was discussed. Besides, challenges and strategies required to control and eradicate human malaria with this emerging and potentially fatal zoonosis were described.

Keywords

Plasmodium knowlesi, Humans, Research, Malaria eradication

Divisions

Parasit

Funders

Ministry of Education Malaysia Long Term Research Grant Scheme (LRGS/1/2018/UM/01/1/2)

Publication Title

Malaria Journal

Volume

21

Issue

1

Publisher

BioMed Central

Publisher Location

CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND

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