Plasmodium knowlesi: The game changer for malaria eradication

Authors

• Wenn Chyau LeeFollow
• Fei Wen CheongFollow
• Amirah AmirFollow
• Meng Yee LaiFollow
• Jia Hui Tan
• Wei Kit Phang
• Shahhaziq Shahari
• Yee-Ling LauFollow

Document Type

Article

Publication Date

5-1-2022

Abstract

Plasmodium knowlesi is a zoonotic malaria parasite that has gained increasing medical interest over the past two decades. This zoonotic parasitic infection is prevalent in Southeast Asia and causes many cases with fulminant pathology. Despite several biogeographical restrictions that limit its distribution, knowlesi malaria cases have been reported in different parts of the world due to travelling and tourism activities. Here, breakthroughs and key information generated from recent (over the past five years, but not limited to) studies conducted on P. knowlesi were reviewed, and the knowledge gap in various research aspects that need to be filled was discussed. Besides, challenges and strategies required to control and eradicate human malaria with this emerging and potentially fatal zoonosis were described.

Keywords

Plasmodium knowlesi, Humans, Research, Malaria eradication

Publication Title

Malaria Journal

Recommended Citation

Lee, Wenn Chyau; Cheong, Fei Wen; Amir, Amirah; Lai, Meng Yee; Tan, Jia Hui; Phang, Wei Kit; Shahari, Shahhaziq; and Lau, Yee-Ling, "Plasmodium knowlesi: The game changer for malaria eradication" (2022). Research Publications (2021 to 2025). 162.
https://knova.um.edu.my/research_publications_2021_2025/162

Divisions

Parasit

Funders

Ministry of Education Malaysia Long Term Research Grant Scheme (LRGS/1/2018/UM/01/1/2)

Volume

21

Issue

1

Publisher

BioMed Central

Publisher Location

CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND